Epididymitis is most common in young men ages 19 to 35. It is most often caused by the spread of a bacterial infection. Infection often begins in the urethra, the prostate, or the bladder. Gonorrhea and chlamydia infections are most often the cause of the problem in young heterosexual men. In children and older men, it is more commonly caused by E coli and similar bacteria. This is also true in homosexual men.
Mycobacterium tuberculosis (TB) can cause epididymitis. Other bacteria (such as Ureaplasma) may also cause the condition.
Amiodarone is a medicine which prevents abnormal heart rhythms. This medicine can also cause epididymitis.
The following increase the risk for epididymitis:
Epididymitis is swelling (inflammation) of the tube that connects the testicle with the vas deferens. The tube is called the epididymis.
Physical exam will show a red, tender lump on the affected side of the scrotum. You may have tenderness in a small area of the testicle where the epididymis is attached. A large area of swelling may develop around the lump.
The lymph nodes in the groin area may be enlarged. There may also be discharge from the penis. A rectal exam may show an enlarged or tender prostate.
These tests may be performed:
Epididymitis most often gets better with antibiotic treatment. There are no long-term sexual or reproductive problems in most cases. However, the condition may return.
Sudden and severe pain in the scrotum is a medical emergency. You need to be seen by a provider right away.
You can prevent complications if you get diagnosed and treated early.
Your provider may prescribe antibiotics before a surgery. This is because some surgeries could raise the risk for epididymitis. Practice safe sex. Avoid multiple sexual partners and use condoms. This may help prevent epididymitis caused by sexually transmitted diseases.
Epididymitis may begin with:
The testicle area will get more sensitive to pressure. It will become painful as the condition progresses. An infection in the epididymis can easily spread to the testicle.
Other symptoms include:
Less common symptoms are:
Symptoms of epididymitis may be similar to those of testicular torsion, which requires emergent treatment.
Your health care provider will prescribe medicine to treat the infection. Sexually transmitted infections need antibiotics. Your sexual partners should also be treated. You may need pain medicines and anti-inflammatory medicines.
If you are taking amiodarone, you may need to lower your dose or change your medicine. Talk with your provider.
To ease discomfort:
You will need to follow-up with your provider to make sure the infection has cleared completely.
Call your provider if you have symptoms of epididymitis. Go to the emergency room or call the local emergency number (such as 911) if you have sudden, severe testicle pain or pain after an injury.
Geisler GM. Diseases caused by chlamydiae. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 318.
Nickel JC. Inflammatory and pain conditions of the male genitourinary tract. In: Wein AJ, Kavoussi LR, Partin AW, Peters CA, eds. Campbell-Walsh Urology. 11th ed. Philadelphia, PA: Elsevier; 2016:chap 13.
Review Date: 10/4/2016
Reviewed By: Jennifer Sobol, DO, urologist with the Michigan Institute of Urology, West Bloomfield, MI. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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